The Platynereis larval connectome and diversity of sensory cells and circuits

2nd Platynereis Satellite meeting
24 - 25th of June 2024

Gáspár Jékely

Centre for Organismal Studies, Heidelberg University

@jekely@biologists.social

Neuronal circuit bases of larval behaviour



phototaxis

startle response

crawling

Platynereis larval and juvenile stages

Whole-body connectome of a three-day-old larva

Whole-body connectome of a three-day-old larva

Annotation of all cell types

Information flow from sensors to effectors

Sensory cell synapses

Sensory cells project ipsilaterally

Sensory cells in the head



Connections of head sensory cells

Postural control system

Shared circuit of eyespot and eyes

MNant circuit


Mushroom bodies


The mechanosensory girdle


Chaetal mechanoreceptors



Evolution by duplication and divergence

Pygidial cells

Functional analysis of circuits

Acknowledgements

  • Sanja Jasek
  • Alexandra Kerbl
  • Emily Savage
  • Simone Wolters
  • Lara Keweloh
  • Kevin Urbansky
  • Karel Mocaer
  • David Hug
  • Benedikt Dürr
  • Ira Maegele
  • Emelie Brodrick (Exeter)

Former lab members

  • Kei Jokura, Luis A. Bezares-Calderón, Luis A. Yanez-Guerra, Victoria Moris, Daniel Thiel, Albina Asadulina, Cameron Hird, Adam Johnstone, Markus Conzelmann, Nadine Randel, Philipp Bauknecht, Martin Gühmann, Cristina Pineiro-Lopez, Nobuo Ueda, Aurora Panzera, Csaba Verasztó, Elizabeth Williams