Regulation of the ciliary rhythm in Platynereis larvae across time scales
Rhythms@Sea Symposium, SZN
Nov 6, 2023
Platynereis dumerilii
- breeding culture, full life-cycle
- embryos daily, year round
- genome sequence
- microinjection, transgenesis
- neuron-specific promoters and antibodies
- knock-out lines
- neuronal connectome
- whole-body neuronal activity imaging
- whole-animal pharmacology by bath application 😎
Whole-body coordination of ciliary arrests
Ciliary rhythm at the circadian scale - day/night regulation of arrests
Ciliary arrests are modulated by many neuromodulators
Whole-body vEM reconstruction of a 3d Platynereis larva
Ciliary beating increases under pressure
Pressure is sensed by photoreceptors with ramified cilia
Circuitry of ciliary photoreceptors
Myoinhibitory peptide increases closures during settlement
Mushroom body inputs to the ciliomotor system
Acknowledgements
- Emelie Brodrick
- Cyrielle Kaltenrieder
- Réza Shahidi
- Milena Marinkovic
- Daniel Thiel
- Sanja Jasek
- Cameron Hird
- Rebecca Turner
- Luis A. Bezares-Calderón
- Kei Jokura
- Luis Yanez Guerra
- Alexandra Kerbl
Former lab members
- Albina Asadulina
- James Beard
- Markus Conzelmann
- Nadine Randel
- Philipp Bauknecht
- Martin Gühmann
- Cristina Pineiro-Lopez
- Nobuo Ueda
- Aurora Panzera
- Csaba Verasztó
- Elizabeth Williams
